| Wednesday, 23 Nov 2011 |
| HOME TEAM | | SCORE | | AWAY TEAM |
| CSKA Moscow |
| 0 - 2 |
| Lille |
| Napoli |
| 2 - 1 |
| Manchester City |
| Bayern Munchen |
| 3 - 1 |
| Villarreal |
| Trabzonspor |
| 1 - 1 |
| Internazionale |
| Otelul Galati |
| 2 - 3 |
| Basel |
| Manchester United |
| 2 - 2 |
| Benfica |
| Real Madrid |
| 6 - 2 |
| Dinamo Zagreb |
| Olympique Lyon |
| 0 - 0 |
| Ajax |
| Thursday, 24 Nov 2011 |
| HOME TEAM | | SCORE | | AWAY TEAM |
| Zenit |
| 0 - 0 |
| APOEL |
| BATE |
| 0 - 1 |
| Viktoria Plzen |
| Bayer Leverkusen |
| 2 - 1 |
| Chelsea |
| Valencia |
| 7 - 0 |
| Genk |
| Olympique Marseille |
| 0 - 1 |
| Olympiakus Piraeus |
| Arsenal |
| 2 - 1 |
| Borussia Dortmund |
| Shakhtar Donetsk |
| 0 - 2 |
| Porto |
| AC Milan |
| 2 - 3 |
| Barcelona |
*(GMT+07:00) Bangkok, Hanoi, Jakarta
