| Wednesday, 22 Sept 2010 |
| HOME TEAM | | TIME | | AWAY TEAM |
| Brentford | | 01:45 | | Everton |
| Portsmouth | | 01:45 | | Leicester City |
| Stoke City | | 01:45 | | Fulham |
| Tottenham Hotspur | | 01:45 | | Arsenal |
| Milwall | | 01:45 | | Ipswich Town |
| Wolverhampton | | 01:45 | | Notts County |
| Burnley | | 01:45 | | Bolton Wanderers |
| Birmingham City | | 01:45 | | Milton Keynes Dons |
| Sunderland | | 01:45 | | West Ham United |
| Peterborough United | | 01:45 | | Swansea City |
| Thursday, 23 Sept 2010 |
| HOME TEAM | | TIME | | AWAY TEAM |
| Chelsea | | 01:45 | | Newcastle United |
| Aston Villa | | 01:45 | | Blackburn Rovers |
| Scunthorpe United | | 01:45 | | Manchester United |
| Wigan Athletic | | 01:45 | | Preston North End |
| Liverpool | | 02:00 | | Northampton Town |
| West Bromwich Albion | | 02:00 | | Manchester City |
*(GMT+07:00) Bangkok, Hanoi, Jakarta
