| | | SCORE | | |
| Aris | | 0 - 3 | | Manchester City |
| Aris |
| 0 - 0 |
| Manchester City |
| Manchester City |
| 3 - 0 |
| Aris |
| Rubin Kazan | | 2 - 4 | | Twente |
| Rubin Kazan |
| 0 - 2 |
| Twente |
| Twente |
| 2 - 2 |
| Rubin Kazan |
| Metalist | | 0 - 6 | | Bayer Leverkusen |
| Metalist |
| 0 - 4 |
| Bayer Leverkusen |
| Bayer Leverkusen |
| 2 - 0 |
| Metalist |
| Napoli | | 1 - 2 | | Villarreal |
| Napoli |
| 0 - 0 |
| Villarreal |
| Villarreal |
| 2 - 1 |
| Napoli |
| Anderlecht | | 0 - 5 | | Ajax |
| Anderlecht |
| 0 - 3 |
| Ajax |
| Ajax |
| 2 - 0 |
| Anderlecht |
| Lech Poznan | | 1 - 2 | | Sporting Braga |
| Lech Poznan |
| 1 - 0 |
| Sporting Braga |
| Sporting Braga |
| 2 - 0 |
| Lech Poznan |
| Besiktas | | 1 - 8 | | Dynamo Kyiv |
| Besiktas |
| 1 - 4 |
| Dynamo Kyiv |
| Dynamo Kyiv |
| 4 - 0 |
| Besiktas |
| Benfica | | 4 - 1 | | Stuttgart |
| Benfica |
| 2 - 1 |
| Stuttgart |
| Stuttgart |
| 0 - 2 |
| Benfica |
| BATE | | 2 - 2 | | PSG |
| BATE |
| 2 - 2 |
| PSG |
| PSG |
| 0 - 0 |
| BATE |
| PAOK | | 1 - 2 | | CSKA Moskva |
| PAOK |
| 0 - 1 |
| CSKA Moskva |
| CSKA Moskva |
| 1 - 1 |
| PAOK |
| Sevilla | | 2 - 2 | | Porto |
| Sevilla |
| 1 - 2 |
| Porto |
| Porto |
| 0 - 1 |
| Sevilla |
| Rangers | | 3 - 3 | | Sporting Lisbon |
| Rangers |
| 1 - 1 |
| Sporting Lisbon |
| Sporting Lisbon |
| 2 - 2 |
| Rangers |
| Sparta Praha | | 0 - 1 | | Liverpool |
| Sparta Praha |
| 0 - 0 |
| Liverpool |
| Liverpool |
| 1 - 0 |
| Sparta Praha |
| Basel | | 3 - 4 | | Spartak Moskva |
| Basel |
| 2 - 3 |
| Spartak Moskva |
| Spartak Moskva |
| 1 - 1 |
| Basel |
| Young Boys | | 3 - 4 | | Zenit |
| Young Boys |
| 2 - 1 |
| Zenit |
| Zenit |
| 3 - 1 |
| Young Boys |
| Lille | | 3 - 5 | | PSV |
| Lille |
| 2 - 2 |
| PSV |
| PSV |
| 3 - 1 |
| Lille |
UEFA Europa League - 16th Finals - Aggregate Results
