| Friday, 1 Oct 2010 | ||||
| HOME TEAM | SCORE | AWAY TEAM | ||
| Rapid Wien |  | 1 - 2 |  | Besiktas |
| CSKA Sofia |  | 0 - 1 |  | Porto |
| Steaua Bucureşti |  | 3 - 3 |  | Napoli |
| Utrecht |  | 0 - 0 |  | Liverpool |
| PSG |  | 2 - 0 |  | Karpaty |
| Borussia Dortmund |  | 0 - 1 |  | Sevilla |
| Sampdoria |  | 1 - 0 |  | Debrecen |
| Metalist |  | 0 - 2 |  | PSV |
| OB |  | 1 - 2 |  | Stuttgart |
| Young Boys |  | 2 - 0 |  | Getafe |
| Zenit St. Petersburg |  | 4 - 2 |  | AEK |
| Hajduk Split |  | 1 - 0 |  | Anderlecht |
| CSKA Moskva |  | 3 - 0 |  | Sparta Praha |
| Sporting Lisbon |  | 5 - 0 |  | Levski Sofia |
| Gent |  | 1 - 1 |  | Lille |
| Atlético Madrid |  | 1 - 1 |  | Bayer Leverkusen |
| Rosenborg |  | 2 - 1 |  | Aris |
| Manchester City |  | 1 - 1 |  | Juventus |
| Lech Poznan |  | 2 - 0 |  | Salzburg |
| Palermo |  | 1 - 0 |  | Lausane Sports |
| BATE |  | 4 - 1 |  | AZ |
| Sheriff |  | 2 - 0 |  | Dynamo Kyiv |
| PAOK |  | 1 - 0 |  | Dinamo Zagreb |
| Villarreal |  | 2 - 1 |  | Club Brugge |
*(GMT+07:00) Bangkok, Hanoi, Jakarta
